I want to know the process of bone formation.?

7 Answers

• Osteogenesis is the process of laying down new bone material by osteoblasts. It occurs in two different ways: Either by Intramembranous Osteogenesis (see intramembranous ossification), which is the direct laying down of bone into the primitive connective tissue (mesenchyme), or by Endochondral Osteogenesis (see endochondral ossification) which involves a cartilage precursor.

  The first step in the process is the formation of bone spicules which eventually fuse with each other and become trabeculae. The periosteum is formed and bone growth continues at the surface of trabeculae. Much like spicules, the increasing growth of trabeculae result in interconnection and this network is called woven bone. Eventually, woven bone is replaced by lamellar bone.

  Process Overview

  Mesenchyme cell in the membrane become osteochondral progenitor cell

  osteochondral progenitor cell specialized to become osteoblast

  Osteoblast produce bone matrix and surrounded collagen fiber and become osteocyte

  As the result process trabeculae will develop

  Osteoblast will trap trabeculae to produce bone

  Trabeculae will join together to produce spongy cell

  Cells in the spongy cell will specialize to produce red bone marrow

  Cells surrounding the developing bone will produce periosteum

  Osteoblasts from the Periosteum on the bone matrix will produce compact bone

  Ossification is a medical term that is synonymous with bone tissue formation. Endochondral ossification and intramembranous ossification are two processes resulting in the formation of normal, healthy bone tissue.[1] Heterotopic ossification is a process resulting in the formation of bone tissue, that is often atypical, at an extraskeletal location. Calcification is a medical term that is often confused with ossification. Calcification is synonymous with the formation of calcium-based salts and crystals within cells and tissue. Calcification is a process that occurs during ossification, but not vice versa.

  Calcification is the process in which calcium salts build up in soft tissue, causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification.

• Osteogenesis Is The Process Of

• Bone formation (osteogenesis) begins during prenatal development and persists throughout adulthood. The bones of infants and children are softer than in adults because it has not yet been ossified (the process of synthesizing cartilage into bone). There are two ways in which osteogenesis occurs: intramembranous ossification and endochondral ossification. Both types form by replacing existing cartilage however differ in the method they go about doing it. Two types of cells that are of great importance in the process are osteoblasts and osteoclasts. Osteoblasts, used mainly in intramembranous ossification, are the specialized cells in bone tissue that deposit calcium into the protein matrix of bone (collagen). Osteoclasts, used in endochondral ossification, dissolve calcium previously stored away in bone and carry it to tissues whenever needed. One third of all of the bone’s components is collagen; a flexible, gelatin-like matrix. Bones formed during intramembranous formation are called membranous bones, or occasionally dermal bone, and bones formed during endochondral formation are called cartilage bone.Intramembraneous ossification is the formation of bone on, or in, fibrous connective tissue (which is formed from condensed mesenchyme cells). Intramembraneous ossification is the process used to make flat bones such as the mandible and flat bones of the skull.

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  RE:

  I want to know the process of bone formation.?

  How it is controlled and the minerals required.

• The process of bone resorption by the osteoclasts releases stored calcium into the systemic circulation and is an important process in regulating calcium balance. As bone formation actively fixes circulating calcium in its mineral form, removing it from the bloodstream, resorption actively unfixes it thereby increasing circulating calcium levels. These processes occur in tandem at site-specific locations.

• Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals.Bone tissue is a type of dense connective tissue. Because bones come in a variety of shapes and have a complex internal and external structure they are lightweight, yet strong and hard, in addition to fulfilling their many other functions. One of the types of tissue that makes up bone is the mineralized osseous tissue, also called bone tissue, that gives it rigidity and a honeycomb-like three-dimensional internal structure. Other types of tissue found in bones include marrow, endosteum and periosteum, nerves, blood vessels and cartilage.

• Osteogenesis