“Your experimental results indicate that antibiotics such as tetracycline, streptomycin, and chloramphenicol have a broad spectrum of activity against prokaryotic cells. Why do these antibiotics lack inhibitory activity against eukaryotic cells such as fungi?”
These antibiotics specifically act on bacterial cell walls. Euks don’t have cell walls. Further, the cell walls of bacteria are different from those of plants and fungi. Plant/fungi walls are made of cellulose and chitin, whereas bacterial walls are made of peptidoglycan.
Antibiotics inhibit the synthesis of peptidoglycan. Without cell walls, bacteria die.
Microbiology is the learn of microorganisms, that are unicellular or cellular-cluster microscopic organisms. This contains eukaryotes which contain fungi and protists, and prokaryotes which contain micro organism and specific algaes. Viruses, even with the undeniable fact that no longer strictly classed as dwelling organisms, are additionally studied. Microbiology is a extensive term which contains many branches like bacteriology, virology, mycology, parasitology and others. a man or woman who specializes interior the portion of microbiology is named a microbiologist. although lots is now universal interior the sector of microbiology, advances are being made in many situations. the main worry-unfastened estimates advise that we’ve studied basically a pair of million% of all the microbes in any given ecosystem. for that reason, in spite of the fact that over 3 hundred years have exceeded because of the fact the invention of microbes, the sector of microbiology is obviously in its infancy relative to different organic and organic disciplines which contain zoology, botany and entomology.
basicallly its the difference between prokaryotes and eukaryotes….antibiotics effect things like the cell membranes of prokaryotes, their polymerases, their ribosomes, etc.. their is a large difference between these things in prokaryotes and eukaryotes i.e. ribosome size, type of cell membranes etc…this also brings up the topic of selective toxicity and why it is hard to achieve this in eukaryotic disease i.e. malaria (drugs have adverse effects, may make you sick / weird dreams/ all sorts of stuff)